• br Ghrelin actions in the central

  2022-10-03

  

  Ghrelin actions in the central nervous system Ghrelin induces thymopoeisis GHS-R1a is expressed in immune cells, including thymocytes and T-cells [13]. Infusion of ghrelin increases the number of thymocytes and thymus size in 14-, 20-, and 24-month-old mice, and with decreased thymic adiposity

• FPR activation stimulates multiple signal

  2022-10-02

  

  FPR1 activation stimulates multiple signal transduction pathways responsible for various neutrophil functions, such as adhesion, chemotaxis, phagocytosis, SNOG synthesis of secretory granules, and superoxide anion radical (O2) production, which contribute to the physiological inflammatory response

• One PKC target that controls

  2022-10-02

  

  One PKC target that controls cortical DL-Dithiothreitol mg structure is a well-known actin crosslinking protein, myristoylated alanine-rich C-kinase substrate (MARCKS). MARCKS cross-links actin and binds PIP2 and this binding activity is regulated by PKC phosphorylation [82]. Activation of PKC rele

• The organ culture method has previously shown to be

  2022-10-02

  

  The organ culture method has previously shown to be a suitable model for investigations of receptor upregulation on vascular smooth muscle cells (Adner et al., 1996). In our study, the organ culture method was applied in order to examine whether LPS from P.g. was capable of altering the gene express

• Adenine In cancer cells HIF upregulates HK II expression

  2022-10-02

  

  In cancer cells, HIF-1α upregulates HK-II expression by binding to the hypoxia-responsive element in the HK-II promoter region to adapt to hypoxic conditions [20]. In the present study, we observed that mangiferin transiently increased HIF-1α expression in endothelial cells, suggesting another possi

• dormin In order to determine whether NF B could interact

  2022-10-01

  

  In order to determine whether NF-κB could interact with GSTP1-1 promoter, we performed EMSA. One NF-κB like (−98κB) binding site was previously described in the GSTP1-1 promoter as a regulator element. However, few data about this site have been published and its role in the GSTP1-1 gene regulation

• Decreasing GSK activity has therapeutic benefits

  2022-10-01

  

  Decreasing GSK-3β activity has therapeutic benefits in animal model of colitis [45] and traumatic Sumatriptan injury [46] and ischemia/reperfusion injury [47,48]. In brain, activation of GSK-3β promotes Aβ toxicity by elevating APP expression and its amyloidogenic cleavage, and by dysregulating Aβ

• br Acknowledgements We thank the following individuals for

  2022-09-30

  

  Acknowledgements We thank the following individuals for notable contributions to this work: Dr. Ruth Wood, Dr. Alan Watts, Dr. Casey Donovan, Andrea Suarez, Emily Nakamoto, Allison Apfel, April Banayan, and Jonathan Cheung. This study was supported by the National Institute of Health grants, DK10

• c-Myc Peptide We are aware that the

  2022-09-30

  

  We are aware that the classical biochemical view is centered on the local concentrations of specific ion and molecules rather than on cell electric potentials. However, important downstream processes can be influenced by acting locally on these potentials because they regulate the conductance of the

• The role of cell to cell interactions

  2022-09-30

  

  The role of cell-to-cell interactions in coordinating the cells’ behaviour to ensure an appropriate anterior pituitary hormone response is receiving increasing attention. Anterior pituitary (+)-Catechin hydrate interact with neighbouring cells through junctional complexes. As their name implies, the

• As mentioned earlier two different isoforms of TFE have been

  2022-09-30

  

  As mentioned earlier two different isoforms of TFE3 [16] have been reported viz. the full length (TFE3L) and smaller (TFE3S) without exon 1&2. TFE3S lacks an N-terminal acidic activation domain which is present in TFE3L hence is a dominant negative form of TFE3L [51]. This dominant negative feature

• Stimulation of FPR by bacterial N formyl peptides

  2022-09-30

  

  Stimulation of FPR by bacterial N-formyl peptides induces basophil and mast 1-Azakenpaullone release of immunogenic compounds such as histamine [21], [31]. Furthermore, we demonstrated that histamine plays a role in F-MITs-induced sepsis-like symptoms since cimetidine, a histamine H2-receptor antago

• br Acknowledgments We apologize for the omission of

  2022-09-30

  

  Acknowledgments We apologize for the omission of primary citations owing to space limitations. This work was supported by grants from National Natural Science Foundation of China (81772801 and 81472455 to C.D.), the Key Program of Zhejiang Provincial Natural Science Foundation (LZ17H160002 to C.D

• retinoic acid receptor Introduction Thrombotic disorders inc

  2022-09-29

  

  Introduction Thrombotic disorders including ischemic heart disease, deep venous thrombosis, and ischemic stroke represent one of the most common causes of death in the world [1]. All these conditions relate to states accompanied by a shift of hemostasis balance into a coagulation side because of va

• Electrochemical techniques have attracted broad

  2022-09-29

  

  Electrochemical techniques have attracted broad attention for their outstanding advantages, such as satisfactory sensitivity and convenient operation. Nowadays, nucleic Thiamet G nanostructures such as DNA tetrahedron structure, nucleic acid-mimicking structure, exhibit noticeable application in the

15143 records 308/1010 page Previous Next First page 上5页 306307308309310 下5页 Last page