• MIP binds to three different receptors CCR CCR and

  2019-06-20

  

  MIP-1α binds to three different receptors: CCR1, CCR5 and CCR9. CCR1 and CCR5 are expressed on MM G-36 and stromal cells. Inhibitors to CCR1 and CCR5 have been used to delineate the roles of each receptor in the myeloma bone marrow microenvironment[69]. Menu and colleagues demonstrated that MM cell

• LQTS is classified into subtypes LQT

  2019-06-20

  

  LQTS is classified into subtypes LQT1 to LQT13 based on the site of genetic mutation. Each type possesses distinct clinical characteristics and a different prognosis. Treatment choice depends partly on individual phenotype and partly on genotype. Among Asian countries, several reports have been publ

• br Results br Discussion We identified a novel heterozygous

  2019-06-20

  

  Results Discussion We identified a novel, heterozygous nonsense SCN5A mutation, Q779X, in a family with overlapped phenotype with progressive conduction defects and BrS. The proband suffered from SSS at the age of three, and subsequent ventricular fibrillation with a coved type Brugada ECG pat

• Fourth the enormous investment in

  2019-06-20

  

  Fourth, the enormous investment in accessible medicines and medical products without investment in checking their quality is profoundly illogical. WHO estimates that only 7% of sub-Saharan countries had a “moderately functioning MRA”. We cannot expect the world\'s medicine supply to improve without

• En definitiva se trataba de buscar un origen de

  2019-06-20

  

  En definitiva, se trataba de buscar un “origen” de la literatura y cultura latinoamericana, no afincado en las textualidades del siglo xix o en un momento tar-docolonial, sino en aquellos textos “fundantes” en los que todo parecía posible: las crónicas de conquistadores y soldados, los conmovedores

• The diagnosis of PTC based

  2019-06-20

  

  The diagnosis of PTC, based on the Modified Dandy Criteria, is made when a patient exhibits an elevated LP opening pressure above 25cm H20 with normal CSF composition and radiologic findings, and no other explanation for the rise in intracranial pressure [6]. The most common presenting symptom occur

• For most health care professionals infectious disease modell

  2019-06-20

  

  For most health-care professionals, infectious-disease modelling is something of a black box. One can see the input assumptions (ie, what goes in) and the outputs (ie, what comes out), but what happens in between seems close to magic. Given their complexity, to understand any one of the models used

• br Methods br Results In patients we analyzed sites

  2019-06-20

  

  Methods Results In 22 patients, we analyzed 82 sites at which HFS was delivered. We identified 57 GP-positive sites on the basis of a vagal response (19 at the MTGP, 18 at the SLGP, and 20 at the ARGP) and 25 GP-negative sites. After delivery of radiofrequency CI 976 (30–35W for 30s) to the 5

• br Disclosures br Acknowledgments br Introduction Long term

  2019-06-20

  

  Disclosures Acknowledgments Introduction Long-term endurance sports have recently been recognized as one of the risk factors for atrial fibrillation (AF) [1–8]; widely accepted risk factors for AF include age, hypertension, diabetes mellitus, structural Gedunin disease, hyperthyroidism, ob

• br Materials methods br Results br Discussion The

  2019-06-20

  

  Materials-methods Results Discussion The general statement that can be concluded from the studies comparing the utility of 18F–NaF PET or PET/CT with 99mTc- MDP whole body bone scintigraphy is that 18F–NaF PET/CT generally has a higher sensitivity and specificity than bone scan. Higher upta

• Under conditions of high cholesterol consumption

  2019-06-20

  

  Under conditions of high cholesterol consumption, an appreciable fraction of cholesterol in bile is derived from the diet through the chylomicron pathway to the liver. Dietary cholesterol reaches the liver through the intestinal lymphatic routes as of chylomicrons, and subsequently, chylomicron remn

• The great American epidemiologist Bill Silverman taught

  2019-06-20

  

  The great American epidemiologist Bill Silverman taught us that the road to hell is paved with good intentions. From 1942, during a 12-year period, more than 10 000 infants were blinded through retinopathy of prematurity because paediatricians recommended a minor increase in the concentration of sup

• En una de las acciones de refriega

  2019-06-20

  

  En una de las acciones de refriega, los indígenas alzaron Sennoside C mano a un sargento y lo bajaron por las laderas de la montaña en el sector de Alto Berlín, donde los soldados custodiaban torres de comunicación como muestra de que no deseaban actores armados legales o ilegales en la zona. Esto c

• Non communicable disease behavioural risk factors such

  2019-06-19

  

  Non-communicable disease behavioural risk factors such as tobacco smoking, heavy alcohol consumption, physical inactivity, and unhealthy eating are socially patterned in high-income countries, with individuals of low socioeconomic status generally experiencing a higher burden of risk factors. Howeve

• br We have reviewed the issues

  2019-06-19

  

  We have reviewed the issues and arguments presented by Wang et al. In fact, we have well-clarified these issues in “Discussion” section of our original article. The aim of our study was to investigate the expression of maternal antineuronal AT13148 and their role in childhood autism spectrum dis

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