• Disclosure br Pericardial disorders constitute a

  2018-11-09

  

  Disclosure Pericardial disorders constitute a relatively common cause of heart disease accounting for 0.1–0.2% of all hospital admissions (). From a clinical point of view pericardial syndromes encompass acute pericarditis (including relapses in the setting of recurrent forms), chronic constricti

• buy GSK2606414 Research is essential to improve

  2018-11-09

  

  Research is essential to improve the evidence buy GSK2606414 for policy and clinical practice. The UK research funding landscape has several national and international awarding bodies that invest in pre-clinical (laboratory) science, observational studies, clinical trials, and translational research

• While the precise biological mechanisms by which obesity

  2018-11-09

  

  While the precise biological mechanisms by which obesity and weight loss affect cognitive function are unclear, several plausible pathways exist, including oxidative stress, inflammation, metabolic impairments and vascular dysfunction (Bruce-Keller et al., 2009). Of these potential mechanisms, cereb

• DNA microarray is one of the highly discriminatory sequence

  2018-11-08

  

  DNA microarray is one of the highly discriminatory sequence-based molecular approaches that can quickly and accurately identify the relatedness of organisms by presence/absence of Torin1 in the pathogens. Low density microarray, targeting several major virulence genes has previously been proposed as

• Therefore a major goal remains to

  2018-11-08

  

  Therefore, a major goal remains to understand the complex cellular and molecular network that controls HSC generation and expansion. In fact, HSCs that are mainly slow cycling (Wilson et al., 2008) and reside in the bone marrow during the entire life of an individual, are not generated there. They a

• To further determine the generality of

  2018-11-08

  

  To further determine the generality of our finding that iPSCs harbor unique transversion-predominant point mutation profiles (Figure S2D, left), we analyzed previously reported point mutation profiles in 27 different iPSC lines that had been established by various methods, including retrovirus, plas

• br Conflict of interest statement The following are the

  2018-11-08

  

  Conflict of interest statement The following are the supplementary data related to this article. Acknowledgments This research was supported by funds to R.C. and F.C. from the Italian Ministry of Education, University and Research (MIUR). Introduction Besides hematopoietic stem Phos-tag B

• br Materials and methods br Results br Discussion Attempts t

  2018-11-08

  

  Materials and methods Results Discussion Attempts to identify a resident adult stem cell in the kidney have led to the identification of CD133+/CD24+ cells in the Bowman\'s capsule (Sagrinati et al., 2006) or CD133+ cells in the renal cortex (Bussolati et al., 2005) and in the renal inner m

• A paradoxical outcome of dietary SPI

  2018-11-08

  

  A paradoxical outcome of dietary SPI exposure is the shorter latency of Wnt1-generated mammary tumors, despite the significant reduction in tumor incidence in SPI-fed mice. We previously reported that in female rats exposed to SPI and administered with the direct acting carcinogen N-methyl-nitrosour

• Initially it was postulated that a functional FA pathway is

  2018-11-08

  

  Initially it was postulated that a functional FA pathway is a prerequisite for dihydrofolate reductase inhibitor antibacterial to be reprogrammed to the pluripotent stage as reprogramming could only be achieved in FA patient cells after correction of the FA defect (Raya et al., 2009). More recently

• We also observed up regulation of several genes

  2018-11-08

  

  We also observed up-regulation of several genes involved in the inhibition of mesenchymal stem cell lineage differentiation, including EGF, SMURF1, and SMAD4. EGF1 plays a role in maintenance of MSCs by enhancing proliferation and reversibly inhibiting differentiation (Fan et al., 2007; Tamama et al

• citco br Introduction Despite the remarkable

  2018-11-08

  

  Introduction Despite the remarkable progress made during the past half century in the treatment of cardiovascular disease, which is increasingly effective in dealing with the acute stages of life-threatening pathology, they often extend the life of the patient at the expense of generating a chron

• br Microarray based transcriptome analysis Total RNA was iso

  2018-11-08

  

  Microarray-based transcriptome analysis Total RNA was isolated for each sample. For global gene expression analysis on an Illumina microarray platform quality-checked total RNA was used. 500ng RNA for each sample was used. The cRNA synthesis, BeadChip hybridization and scanning were performed by

• br Conclusion In this study we established iNSCs

  2018-11-08

  

  Conclusion In this study, we established iNSCs from two different mouse strains (C3H and C57BL/6). These two iNSCs exhibited distinct reprogramming status in terms of NSC markers expression, silencing of transgenes, and in vitro differentiation potential. Our data suggest that the genetic backgro

• br Materials and methods br Acknowledgments We

  2018-11-08

  

  Materials and methods Acknowledgments We thank Dr. Keisuke Okita and Prof. Shinya Yamanaka for providing the reprogramming plasmids. Additionally, we would like to thank Tina Christoffersen and Birgit Kassow for skillful technical assistance. We acknowledge SHARE\'s Cross Faculty PhD Initiativ

15085 records 986/1006 page Previous Next First page 上5页 986987988989990 下5页 Last page