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A membranaceus Leguminosae is a very well known and widely
2018-11-02
A. membranaceus (Leguminosae) is a very well-known and widely used herbal medicine in China. The dried root of A. membranaceus has a long history of medical use. It is traditionally prepared as a tonic that can improve the functioning of the lungs, adrenal glands, and gastrointestinal tract; increas
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br Methods br Results The results of the
2018-11-02
Methods Results The results of the study are shown in Table 1. There were eight patients with gastric teratomas and all of them were male. Their ages ranged from 1 day to 3.5 years. Seven (87.5%) patients presented in infancy, out of which four (50%) were neonates, while one (12.5%) was a todd
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Histologically a MO lesion passes through
2018-11-02
Histologically, a MO lesion passes through several phases. The varying appearances of MO lesions relate to the histological changes that occur as the disorder progresses. The most crucial diagnostic feature of MO is that the bone maturity occurs from the periphery in a zonal pattern with a fibroblas
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Nuclear factor kappaB NF B
2018-11-02
Nuclear factor-kappaB (NF-κB), as a sensitive transcription factor for regulating the genes responsible for both innate and adaptive immune response, has been identified as a major factor involved in the regulation of pro-inflammatory cytokines such as iNOS and COX-2 [15]. Usually NF-κB resides in t
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Introduction Cancer along with cardiovascular disease CVD
2018-11-02
Introduction Cancer along with cardiovascular disease (CVD) are two of the leading causes of death in the United States; the prevalence of which is also seen at higher rates in developed and industrialized countries. According to the 2010 Cancer Statistics [1], an estimated 1.5 million individuals
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Medicinal plants refer to the class of plants applied for
2018-11-02
Medicinal plants refer to the class of plants applied for therapy or to possess pharmacological actions for human and animal. In morphological aspect, there is no difference between medicinal and others plants, except the characteristics of certain plant to exhibit medicinal benefits. Indonesia comp
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SB 203580 hydrochloride br Remaining questions The presence
2018-11-02
Remaining questions The presence of numerous IAHCs in the SB 203580 hydrochloride raises many questions. (1) Although IAHCs are generally believed to be HSCs, there is an obvious incongruity between the low number of HSCs (E9.5) and HSCs (>E10.5) (Muller et al., 1994; Yokomizo and Dzierzak, 2010
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Cell adhesion to the ECM appears to trigger various intracel
2018-11-02
Cell adhesion to the ECM appears to trigger various intracellular signaling pathways. In addition to proteolytic degradation of amniotic basement membrane components by proteases such as MMP-9, intracellular signaling cascades stimulated by growth factors or cytokines released from cell-cell matrix
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Autografts derived from iPSCs generated by retroviral vector
2018-11-02
Autografts derived from iPSCs generated by retroviral vectors resulted in the accumulation of larger numbers of IBA1+ and CD45+ cells compared with those generated using episomal vectors, probably due to the residual expression of the transgenes (Figure S3). This indicates that residual transgenes c
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br Funding This work was supported by a grant from
2018-11-02
Funding This work was supported by a grant from the Dutch Technology Foundation STW (project 10507). Disclosures Acknowledgments Introduction Acute respiratory distress syndrome (ARDS) is characterized by refractory hypoxemia in patients with bilateral lung infiltrates. The Berlin defin
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Using the combination of a mitogen activated protein kinase
2018-11-02
Using the combination of a mitogen-activated protein kinase kinase (MEK) inhibitor, PD0325901 (PD03), and a glycogen synthase kinase 3 (GSK3) inhibitor, CHIR99021 (CHIR), which will hereafter be referred to as 2i, mouse ESCs (mESCs) are maintained in a ground state (Ying et al., 2008). CHIR activate
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Another remarkable observation of this study is that
2018-11-02
Another remarkable observation of this study is that ASCL1-iN neuraminidase inhibitor are exclusively excitatory. This is surprising, because ASCL1 is not typically associated with the excitatory neuronal lineage during neural development (Bertrand et al., 2002; Fode et al., 2000; Guillemot et al.,
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The WNT signaling pathway is a primary determinant
2018-11-02
The WNT signaling pathway is a primary determinant in assigning an A/P positional identity to NPCs. This instructional cue is imparted early during NPC generation and once this identity is established, it is stable and cannot be altered through exogenous manipulation of the WNT pathway. Using a WNT
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The fact that the in vitro induction of osteogenic different
2018-11-02
The fact that the in vitro induction of osteogenic differentiation leads to sarcoma development from sarcoma iPSCs in concert with EWS-FLI1 expression indicates that these sarcomas arise from osteogenic progenitor cells. However, it is important to note that the withdrawal of EWS-FLI1 in osteosarcom
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br Experimental Procedures br Author
2018-11-02
Experimental Procedures Author Contributions Acknowledgments We thank Drs. Shinichi Aizawa and Frank Costantini for providing mice, and Yuuki Honda, Mayumi Yamamoto, Nanako Goto, Chiaki Kaieda, Masato Tanaka, and Kanako Motomura for excellent technical assistance. This work was supported in
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