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br Author contribution The following are the
2018-11-14
Author contribution The following are the supplementary data related to this article. Acknowledgments We thank Catherine Bresse for her valuable assistance in the statistical analysis. This work was supported by the CIRM grant # RL1-00636-1. Introduction The capacity of human embryonic st
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Introduction The main models used
2018-11-14
Introduction The main models used for describing the structure of woven materials are applicable only to a \"hard\" composite, with solid polymers, for example, hardened epoxy resin [1–6], acting as fillers. Geometric nonlinearity may be neglected for these materials [5,6], since deformations occur
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br Methods Details on baseline
2018-11-14
Methods Details on baseline associations and the primary outcome of the trial have been described elsewhere (Joseph et al., 2014; Joseph, Casapia, & Montresor, 2015). Briefly: Development was assessed at the 12 and 24-month visits using the Bayley Scales of Infant and Toddler Development, Third
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Changes in FA in relation to
2018-11-14
Changes in FA in relation to changes in RD and AD suggest that the greatest change in white matter microstructure was a reduction in RD that led to an increase in FA values. FA is an aggregate index of white matter integrity. It essentially reflects the prominence of diffusion along CX-4945 relativ
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br Results RNA analysis was carried out on NF affected
2018-11-14
Results RNA analysis was carried out on 361 NF1 affected individuals who fulfilled NIH criteria with at least one non pigmentary criterion. Twenty one familial cases with just pigmentary NIH criteria were excluded (14 NF1 mutations (12 missense mutations); 7 SPRED1 mutations). One hundred and sev
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These promising laboratory findings and preclinical results
2018-11-14
These promising laboratory findings and preclinical results inspired the current prospective, randomized, phase I/II clinical trial (, AdiFLAP Trial) designed to evaluate the safety and efficacy of AGTP in patients with chronic myocardial infarction undergoing CABG. Patients were enrolled if they we
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Immunology Compound Library br Materials and Methods br Resu
2018-11-14
Materials and Methods Results Discussion Although aberrant glycosylation is common in cancer and has been linked to PCa progression (Munkley et al., 2016), our understanding of what drives these cancer associated glycan changes has been scant and has relied upon anecdotal observations. Here
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Development of a vaccine to block
2018-11-14
Development of a vaccine to block RBC invasion has proven to be an elusive goal. Much of the effort has been focused on the merozoite surface protein 1 (MSP1) and the apical membrane antigen 1 (AMA1). Multiple preclinical vaccine studies have demonstrated, using growth inhibition assays (GIA), that
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The public health implications of our study are
2018-11-14
The public health implications of our study are significant, shedding light on the overarching question of whether iron supplements cause harm. We acknowledge that in vitro parasite growth might not translate directly to malaria susceptibility. Yet there are no other viable alternatives for addressi
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br Human respiratory syncytial virus RSV
2018-11-14
Human respiratory syncytial virus (RSV) is the most frequent cause of lower respiratory tract infections in infants and young children worldwide and also an important pathogen in elderly. Millions of patients get hospitalized and up to 200,000 children die each year due to an RSV infection (). Des
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Sampling by nasosorption has been carried out in children wi
2018-11-14
Sampling by nasosorption has been carried out in children with rhinitis (Chawes et al., 2010), neonates (Folsgaard et al., 2012), and after nasal allergen challenge (Scadding et al., 2012, 2015; Nicholson et al., 2011; Leaker et al., 2017). Nasal lavage causes considerable dilution of nasal mediator
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br Funding sources The Lundbeck Foundation Denmark R
2018-11-14
Funding sources The Lundbeck Foundation Denmark (R124-A11485 and R181-2014-3372) and Carlsberg Foundation Denmark (CF14-0561) are acknowledged for grants enabling the analysis (TBB grants). The overseas collaboration was supported by the Knud Hojgaard Foundation Denmark (j.nr. 45.462), the Oticon
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br Experimental design The dataset presented here was
2018-11-14
Experimental design The dataset presented here was obtained from using the label-free proteomic analysis of three different strains of Prototheca species, P. zopfii genotype 1, genotype 2 and P. blaschkeae representing non-infectious, infectious and moderately infectious strains, respectively. In
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The spectral power at the neonatal peak i
2018-11-14
The spectral power at the neonatal peak (i.e., 0.0056Hz) showed largely uniform decreases during the first year (Fig. 2D). However, the developmental trend at the peak-frequency of 2-year-olds (i.e., 0.0278Hz) showed spatially dependent patterns (Fig. 2E). Specifically, more increases were observed
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cumpli a os en Despu s del
2018-11-13
cumplió 25 años en 2014. Después del número 50, Marta Lamas, su fundadora y directora hasta ese momento, había decidido concluir el ciclo de la revista. No obstante, conscientes de la enorme importancia del proyecto y del reconocimiento que había logrado tanto en México como en Latinoamérica, las in
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