• Although some earlier studies reported significant differenc

  2018-11-01

  

  Although some earlier studies reported significant differences in RFS and PFS rates between risk groups (Xu et al., 2013; Altieri et al., 2012; Van Rhijn et al., 2010), other studies including ours (Fig. 1), found that prediction of both recurrence and progression were poorly discriminated by the EO

• While the human and mouse

  2018-11-01

  

  While the human and mouse PD-1 mutants tend to show generally similar behavior in terms of ligand binding, including the high-affinity A132 mutants, there are some important differences. In THZ1 to murine PD-1, where mutations of residues I134 and E136 result in complete loss of binding to both lig

• Exposure to specific environmental factors increases the ris

  2018-11-01

  

  Exposure to specific environmental factors increases the risk to develop schizophrenia in vulnerable individuals (van Os et al., 2010), thus environmental and genetic factors may both influence age at illness onset in schizophrenia. Accumulated exposures such as obstetric complications, trauma, urba

• br Materials and Methods br Results br Discussion The

  2018-11-01

  

  Materials and Methods Results Discussion The metastatic process comprises a complex cascade in which many growth factors are involved. In order to metastasize, a cancer cell must first escape from its contacts with neighboring BAY 87-2243 cost and the extracellular matrix (ECM) (Frisch and

• equol br Introduction Influenza comprises a substantial port

  2018-11-01

  

  Introduction Influenza comprises a substantial portion of morbidity and mortality caused by acute respiratory infections, which are the fourth leading cause of death and the second highest cause of years of life lost (Organization, 2014; Radin et al., 2012; Nair et al., 2011). Severe influenza di

• br LC MS MS data acquisition br LC MS

  2018-11-01

  

  LC–MS/MS data acquisition LC–MS/MS data analysis, statistical analysis and visualization Data were analyzed and filtered on MaxQuant version 1.2.2 [5] (20ppm error tolerance) with a FDR setting of 1% against the SPROT Yeast database and at a cutoff of at least 2 peptides seen to assign quantit

• br Experimental design materials and

  2018-11-01

  

  Experimental design, materials and methods Data The data reported include supporting information to the phylogenetic analyses of Franchi et al. [1]. They consist of transcript sequences, sequence alignments and comparisons of four apoptosis-related genes identified in the recently-obtained tra

• In terms of substance specific mechanisms of

  2018-11-01

  

  In terms of substance-specific mechanisms of action, nicotine facilitates dopaminergic neurotransmission within sirtuin activators reward pathways via activating nicotinic actylcholine (nAch) receptors, including those located on nerve terminals in VTA projections to the NAcc (D\'souza and Markou,

• br Methods br Results br Discussion br Introduction

  2018-11-01

  

  Methods Results Discussion Introduction The use of institutional care for abandoned or orphaned infants and children has remained a common practice throughout the world (Browne et al., 2006; UNICEF, 2015); however, institutional environments are harmful for healthy physical and psycholog

• br Results and discussion br Conclusions

  2018-11-01

  

  Results and discussion Conclusions Introduction Diaminoazofuraz (DAAzF) is a new kind of furazan derivative synthesized by Sheremeteev [1–5] firstly, and has been considered as a possible ingredient of solid propellants and high explosives due to its potential as an insensitive explosive. D

• A software based GillAc basic

  2018-11-01

  

  A software-based GillAc basic electrochemical system was used to conduct potentiodynamic polarization tests to study the pitting corrosion behaviors of polished samples of friction surfaced coatings. All experiments were conducted in an electrolyte of 0.5M H2SO4 + 0.5M NaCl. Steady state potential w

• br Synthesis procedures br Investigation on studies of HNIW

  2018-11-01

  

  Synthesis procedures Investigation on studies of HNIW and its polymorphs Conclusion In spite of various routes obtained for HNIW synthesis, the present cost of the substance is far high. Modified procedures are required to accomplish cost effectiveness and mass manufacture. Deep view on com

• Through the years aside from

  2018-11-01

  

  Through the years, aside from chemical weapons, warheads have also been designed to generate either fragments or blast shock waves as their primary damage mechanism. Thermobaric explosives (TBXs) have been predominantly used in a blast role (rather than for their fragmentation characteristics) due t

• perifosine br El rock es un

  2018-11-01

  

  El rock es un fenómeno cultural principalmente juvenil, y en él se entraman una serie de símbolos que cobran sentido mediante prácticas y discursos que lo vinculan con actitudes y prácticas de Sin embargo, al analizar dicho fenómeno desde una perspectiva de género, se evidencian complejidades que

• Alumna Rosa Yo tengo una pregunta o

  2018-11-01

  

  Alumna Rosa: Yo tengo una pregunta, o sea, ¿qué significa ser feminista? O sea, si simplemente es estar de acuerdo con todas las causas por las que luchan o realmente es ser activista de cierta forma. Porque varios de aquí, no quiero hablar de ellos, pero pues serían feministas porque están a favor

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