• Two kind systems are currently available to assess the

  2021-12-02

  

  Two kind systems are currently available to assess the nutritional status of cancer patients, one is largely based on some subjective parameters, the other is totally based on the objective parameters. For score systems largely based on some subjective parameters, like Nutritional Risk Screening Sco

• br Conclusion and prospect Small

  2021-12-02

  

  5. Conclusion and prospect Small GTPases are very important regulatory proteins of eukaryotes. They play crucial regulatory function in various movement processes of organism [75], [76], [77]. Different nanoparticles used to investigate the interaction with small GTPases inside ddhUTP structure h

• GSK can function in regulating insulin signaling and glucose

  2021-12-02

  

  GSK-3 can function in regulating insulin signaling and glucose metabolism. Inactivation of GSK-3 activity results in dephosphorylation and activation of GS that leads to improved glucose tolerance. However, there are additional mechanisms that can lead to increases in GS activity and improve insulin

• Tamoxifen is still the most frequently

  2021-12-02

  

  Tamoxifen is still the most frequently used selective estrogen receptor mediator (SERM) in premenopausal women suffering from estrogen receptor positive (ER+) breast carcinomas [15]. Although this therapy has been proven very successful, about 20–30% of ER+ breast tumors will not respond, or acquire

• Overall the multiple nucleic acid

  2021-12-02

  

  Overall, the multiple nucleic DiscoveryProbe™ Inhibitor Library hybridization method is useful for detecting specific transcripts within tissues of nematodes. The present study suggests that Peq-pgp-11 and Peq-pgp-16 mRNAs are expressed in many tissues of Parascaris. Our results indicate that Pgps

• Comparison of dlGALRs deduced amino acid sequences with

  2021-12-01

  

  Comparison of dlGALRs deduced amino Adefovir Dipivoxil receptor sequences with that of human GALRs demonstrate that the GALR1 ortholog sequences have diverged less than those of GALR2. Since often duplicate genes undergo divergent evolution through sub-functionalization, loss or gain of new function

• In a recent study Neelaveni et al revealed that new

  2021-12-01

  

  In a recent study, Neelaveni et al. [47] revealed that new thiazolidinedione derivatives (Fig. 6 a and 6 b) produced dual PPARγ and FFAR1 agonistic activity at micromolar concentrations with insulin sensitizing effects and enhanced insulin secretion from the pancreas. These derivatives were reported

• br Funding The research for this paper is

  2021-12-01

  

  Funding The research for this paper is conducted as part of a PhD thesis at Pasteur Institute of Iran and it was financially supported by Pasteur Institute of Iran and the Iranian Centre for Communicable Diseases. Conflict of interest Acknowledgments Introduction The viral enzyme integr

• Hypoxia HIF and Inflammation Cellular responses to hypoxia

  2021-12-01

  

  Hypoxia, HIF, and Inflammation Cellular responses to hypoxia are essential for life and are now recognized to be dysregulated in a wide range of disease processes. The key players in these pathways are a family of transcription factors, the hypoxia-inducible factors (HIFs; see Glossary), as well as

• We found statistically significant association

  2021-12-01

  

  We found statistically significant association between p95-HER2 levels and hormone receptor status, Ki-67 2,4-Diacetylphloroglucinol and metastatic regions (p = 0.004, [10] investigated the prognostic role of p95-HER2 expression in 483 HER2-positive BC patients and found that p95-HER2 expression wa

• Considering that TGF plays a pivotal role in inflammation re

  2021-12-01

  

  Considering that TGF-β1 plays a pivotal role in inflammation, renal fibrosis, cell growth, differentiation, and apoptosis, it has been viewed as a vital mediator in kidney disease [49,50]. Studies have demonstrated that TGF-β1 is upregulated in both human and experimental kidney diseases [51,52]. TG

• SB525334 Although some PAHs that are human carcinogens have

  2021-12-01

  

  Although some PAHs that are human carcinogens have been found in the sugarcane soot (Zamperlini et al., 1997), there are no data about cancer incidence among sugarcane workers. To the best of our knowledge, this is the first report of an evaluation of internal exposure, comparing the harvesting (whe

• br GSK Glycogen synthase kinase

  2021-12-01

  

  GSK-3 Glycogen synthase kinase-3 (GSK-3) is a ubiquitous serine/threonine kinase that is involved in multiple signaling pathways that are crucial for cellular metabolism and proliferation (Doble and Woodgett, 2003, Frame and Cohen, 2001, Grimes and Jope, 2001, Woodgett, 1990). GSK-3 is known to d

• While published data around the functional significance of

  2021-12-01

  

  While published data around the functional significance of GPR84 are quite sparse, details of signaling pathways initiated by the receptor are even more limited, including in recombinant systems. In recombinant cells, GPR84 activation reportedly leads to Gi pathway activation, resulting in pertussis

• The HIV genome encodes for a variety of

  2021-12-01

  

  The HIV-1 genome encodes for a variety of viral proteins necessary for target cell entry and viral replication. gp120 is an HIV-1 envelope glycoprotein that mediates viral particle entry by binding to cell surface receptor CD4 and co-receptors CXCR4 and/or CCR5 depending on viral tropism. While CXCR

15796 records 514/1054 page Previous Next First page 上5页 511512513514515 下5页 Last page