• Non communicable disease behavioural risk factors such

  2019-06-24

  

  Non-communicable disease behavioural risk factors such as tobacco smoking, heavy alcohol consumption, physical inactivity, and unhealthy eating are socially patterned in high-income countries, with individuals of low socioeconomic status generally experiencing a higher burden of risk factors. Howeve

• br Acknowledgments This study was supported by

  2019-06-24

  

  Acknowledgments This study was supported by a grant from the National Science Council (NSC 98-2314-B-075B-007-MY2). Introduction Many complications may occur following treatment of femoral shaft open fracture such as nonunion, malunion, delay union, bone defect, bone and joint deformity or st

• Since the first description of

  2019-06-24

  

  Since the first description of epicardial VT ablation with percutaneous subxiphoid access in 1996, epicardial mapping and ablation have been widely performed for the treatment of scar-related VT [55]. Svenson et al. reported that Vitamin D3 molecular epicardial VT circuits are particularly common in

• br Conclusion br Conflicts of interest br Clinical case The

  2019-06-21

  

  Conclusion Conflicts of interest Clinical case The worldwide estimated prevalence of cardiovascular implantable electronic device (CIED) infection is 1–2%. Prompt removal of infected devices ensures survival [1–4]. We report successful extraction of a lead from an infected CIED by using an

• br Primary biliary cholangitis Primary biliary cholangitis P

  2019-06-21

  

  Primary biliary cholangitis Primary biliary cholangitis (PBC), previously known as primary biliary cirrhosis, is another rare but devastating immune-mediated cholangiopathy. Similar to PSC, PBC is characterized by portal inflammation leading to fibrosis and eventually cirrhosis. Distinct from PSC

• We propose that the same geospatial statistical techniques

  2019-06-21

  

  We propose that the same geospatial statistical techniques can be applied to HIV. We used these techniques to estimate the number of HIV-infected individuals in Maseru (a health-care district in Lesotho) and establish their geographical location. The district of Maseru is a relatively large area, ab

• This study addresses an important question about

  2019-06-21

  

  This study addresses an important question about whether routine clinic follow-up after medical abortion can be responsively eliminated from service delivery protocols, thus reducing a key barrier to accessing medical abortion. Such a service change could be especially beneficial for women in rural,

• En cualquier caso sabemos que

  2019-06-21

  

  En cualquier caso, sabemos que esta política admonitoria del Corpus obtuvo resultados abundantes que refrendaron la inserción beneficiosa de altas dosis de tremendismo en una catequesis ya no necesariamente diáfana. Incluso contamos con las huellas de una recepción defectuosa del sacramento que llev

• Another mechanism is that J waves represent a

  2019-06-21

  

  Another mechanism is that J waves represent a repolarization abnormality where J waves are created by the transmural voltage gradient [16]. During myocardial ischemia, the membrane ionic currents are known to be augmented, in turn augmenting the transient outward current (Ito). Augmented Ito would r

• Since antithrombotic therapy for patients with AF is rapidly

  2019-06-21

  

  Since antithrombotic therapy for patients with AF is rapidly changing with the increasing use of dabigatran, rivaroxaban, and apixaban, some of the primary issues that will influence the future revision of various guidelines (HRS [Heart Rhythm Society], ESC [European Society of Cardiology], ACC [Ame

• The so called driver hypothesis has been posited in the

  2019-06-21

  

  The so-called driver Nemadectin has been posited in the recent years. Optical mapping studies in isolated sheep hearts have suggested that at least some cases of AF can be maintained by high-frequency reentrant sources (rotors), usually located in the posterior LA, which result in spatially distribu

• Bepridil is a multichannel blocker suggesting that its

  2019-06-21

  

  Bepridil is a multichannel blocker, suggesting that its pharmacological effects on cardiac myocytes are exerted by blocking Na [21], Ca [22], and K [23–25] channels. It has recently been reported that bepridil has a cardioprotective effect [26] by opening ATP-dependent K Proteinase K in mitochondri

• Amongst other anti arrhythmic medications disopyramide class

  2019-06-21

  

  Amongst other anti-arrhythmic medications, disopyramide (class 1A AAM) has anticholinergic side effects such as dry mouth, urinary hesitancy, constipation and exacerbation of conditions like glaucoma and myasthenia gravis. Disopyramide acts by targeting the fast sodium Phosphate Colorimetric Assay K

• br In Sanguinetti et al

  2019-06-21

  

  In 1996, Sanguinetti et al. and Barhanin et al. independently found that, when coassembled with the accessory subunit KCNE1, the KCNQ1 and KCNE1 complex could form a channel that very closely exhibited conductive and kinetic properties similar to that of cardiac IKs[14,56]. Kass and coworkers subs

• br Discussion br Conclusions br

  2019-06-21

  

  Discussion Conclusions Conflicts of interest Introduction Catecholaminergic polymorphic ventricular tachycardia (CPVT) is induced by emotional stress or exercise in patients without organic heart disease and may be polymorphic or bidirectional (Fig. 1) [1–3]. This ventricular arrhythmia

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